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Mild elevations are generally considered to be two to three times the ULN. With some liver diseases, the level can exceed 50 times the ULN. Levels this high are described as deranged.

While it may seem that a high ALT is all that is needed to diagnose liver disease, its relationship to AST can provide valuable clues as to what exactly is going on and whether the issue is acute occurring suddenly and progressing rapidly or chronic long-standing or persistent.

If the liver sustains an acute injury, you can expect to see a sudden spike in the ALT. On the other hand, if a liver disease is slowly progressing, the damage incurred by the liver will gradually affect other organs as well.

As these organs are damaged, the AST will begin to rise. This occurs with diseases like hepatitis C in which long-term liver damage will trigger an ever-expanding array of symptoms involving the kidneys, brain, eyes, skin, and joints referred to as extra-hepatic symptoms.

Depending on which value is elevated and the extent of that elevation, doctors can often get a pretty strong indication as to what disease is involved.

However, a disease cannot be diagnosed by the pattern of elevation alone. The magnitude of elevation described in multiples of the ULN also needs to be evaluated.

It is only when the magnitude is above a certain threshold that the ratio can be considered diagnostic. An LFT may be ordered:. If the lab test is processed on-site, the results can be returned within hours.

Otherwise, your doctor will usually receive the results in anywhere from one to three days. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life.

A review on laboratory liver function tests. Pan Afr Med J. Nonalcoholic fatty liver disease. Am Fam Physician.

Newsome, P. Guidelines on the management of abnormal liver blood tests. More in Hepatitis. Was this page helpful? Thanks for your feedback!

Sign Up. What are your concerns? Article Sources. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles.

A small study found that swapping just one meal a day for a veggie-heavy, low-fat meal can help to lower ALT levels over the course of a month.

An earlier study similarly found that eating a diet lower in calories and carbohydrates was effective for lowering ALT levels in overweight adults with insulin resistance.

Start by trying to eat at least five servings of fresh fruits and vegetables a day. Learn more about treating fatty liver disease with food.

A high ALT level is usually a sign of some type of liver issue. Lowering your ALT will require treating the cause, but certain dietary changes can help.

The liver is a powerhouse organ, performing a variety of tasks that are essential to maintaining good health. Eat these 11 foods for optimal liver….

Fatty liver disease affects nearly one-third of American adults. Diet and lifestyle changes can help reduce your risk for fatty liver disease and….

The foods you consume are important for your liver health. This is especially true if you have a condition like hepatitis C, which can make it…. Taking a liver supplement may be tempting, particularly when hearing the claims of supplement manufacturers.

However, is it really necessary to…. Many things can cause elevated liver enzymes, which is known as transaminitis.

Learn more about the possible causes and when to get help. Drinking enough water can help you burn fat and increase your energy levels.

This page explains exactly how much water you should drink in a day. Excess stress is a common problem for many people. Learn effective ways to relieve stress and anxiety with these 16 simple tips.

If you are one of those who regularly suffers from headaches, here are 18 natural remedies to help you get rid of them.

Happiness can feel impossible, but it's always within reach. We'll break down 25 science-backed habits to help you get you mood on track.

Consume more folate or take folic acid. Make changes to your diet. Written by Adrienne Santos-Longhurst on November 27, What Causes Transaminitis?

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